Compartment syndrome is a true surgical emergency.
It is caused by increasing tissue pressure which prevents capillary blood flow, leading to ischemia in muscle and nerve tissue.
If not treated, tissue necrosis with permanent loss of function may occur.
Compartment syndrome may occur as a result of:
Compartment syndrome occurs in:
Treatment of compartment syndrome requires surgical release of the closed osteo-fascial compartments.
Compartment syndrome is characterized by a rise in pressure within a closed fascial compartment, sufficient to prevent effective capillary perfusion in muscle and nerve tissue.
Normal tissue pressure is 0–10 mm Hg. The capillary filling pressure is essentially diastolic arterial pressure. When tissue pressure approaches the diastolic pressure, capillary blood flow ceases.
Diagnosis requires a high index of suspicion and appreciation of progressively severe symptoms which include the following:
The diagnosis is difficult in patients with:
The illustration shows a distal tibial plafond fracture with swelling and bruising, resulting in fracture blisters. Compartment syndrome should be ruled out.
The signs of an evolving compartment syndrome include:
Effective management of an impending or established compartment syndrome requires:
The most reliable measure of critical intracompartmental perfusion is the muscle perfusion pressure (MPP).
MPP is equal to the difference between diastolic blood pressure (dBP) and measured intramuscular pressure.
This difference in pressure reflects tissue perfusion more reliably than absolute intramuscular pressure.
When the muscle perfusion pressure is reduced to a level at which no capillary perfusion occurs, hypoxia leading to ischemia, and subsequent necrosis will occur.
The critical muscle perfusion pressure depends on the specific anatomical compartment affected.
When the clinical symptoms and signs of compartment syndrome are present, there is no benefit in measuring intracompartmental pressures, and an immediate fasciotomy should be performed.
When it is difficult to confirm the diagnosis, intracompartmental pressure measurement is helpful:
Compartment pressures should be measured at the area of maximal swelling or trauma. There are several techniques for the measurement of intracompartmental tissue pressure:
If the necessary equipment is not available for direct intracompartmental pressure measurement, then the diagnosis must be assumed if there is reasonable clinical suspicion, and fasciotomies must be performed.
In established muscle compartment syndrome, nerve and muscle tissue will become ischemic within less than two hours.
It is therefore of paramount importance that the intracompartmental pressure be released as an emergency intervention.
It is generally accepted that after 6–8 hours of inadequate muscle perfusion pressure (MPP), extensive muscle necrosis is inevitable. Release of the muscle compartments involved will not prevent severe muscle contracture.
Fasciotomy of compartments within which muscle necrosis has already happened has a high risk of infection.
Amputation may be required.
There are several foot compartments; these include:
This illustration shows the compartments at the level of the forefoot.
The medial compartment contains the abductor hallucis and flexor hallucis brevis muscles and is plantar-medial to the first metatarsal.
The superficial compartment contains the flexor digitorum longus and brevis muscles.
The lateral compartment contains the abductor digiti minimi and flexor digiti minimi brevis and is on the inferolateral surface of the fifth metatarsal.
The adductor or deep compartment is located in the plantar forefoot, containing the oblique head of the adductor hallucis muscle.
The four interossei compartments are dorsally located between the metatarsals, and each includes dorsal and plantar interosseus muscles.
The calcaneal compartment contains the quadratus plantae muscle.
Compartment syndrome of the foot may lead to:
Fasciotomy may be effective in reducing the risk of intrinsic toe contractures but may lead to secondary infection and challenging soft-tissue coverage.
The approaches for compartment decompression generally include two dorsal incisions for access to forefoot/interossei compartments, one medial incision for decompression of the calcaneal, medial, and superficial compartments, and one lateral incision for the lateral compartments.
The two dorsal incisions are placed, one over the second metatarsal shaft and one over the fourth metatarsal shaft.
The fasciae of the interosseous muscles are opened dorsally. The muscle is stripped off the second metatarsal medially, and the fascia of the adductor compartment is opened bluntly deep within the first interspace.
The medial incision is made within the foot's arch, along the muscle body of the abductor hallucis.
Dissection is continued both dorsal and plantar to the abductor hallucis muscle, which releases the medial, deep, and superficial compartments.
The lateral incision is made immediately plantarward of the fifth metatarsal.
The abductor digiti minimi compartment is released.
After a fasciotomy or fasciotomies have been performed, skin edges retract and can become difficult to close. Careful use of elastic retention sutures (elastic vessel loops woven through skin staples) can help counteract excessive skin contraction while still allowing the decompressed muscles to swell without any undue tension over them. Temporary coverage of the wounds can be obtained with either a wound vacuum-assisted closure (VAC) device or coverage with saline-soaked gauze bandages. These dressings or the wound VAC can be kept on until the patient returns for an attempt at secondary closure.
If the swelling of the limb adequately decreases upon subsequent return to the operating room, primary closure of the fasciotomy wounds can occur. It is important not to perform primary closure if there is any concern about persistent swelling; secondary coverage options exist. In many instances, application of an incisional wound vac can enhance wound healing.
If persistent swelling exists but wound closure is necessary, particularly for fractures that have been fixed, secondary wound coverage options are necessary. These include split thickness skin grafting, muscle flaps, or musculocutaneous flaps. In many instances wound vacs are employed to enhance wound healing.
It is imperative to cover fractures that have been fixed in a timely manner so as to minimize the risk of subsequent infection.
It is important to splint the foot and ankle in a neutral position to maintain a plantigrade foot, particularly if any muscle damage has occurred, as flexion contractures may develop. This can be done with a well-padded plaster back-slab, or with the extension of an external fixator to the foot. Maintain toe mobility with passive stretching.
Once the wounds have healed, assisted and active range of motion exercises are started to avoid the development of contractures. Flexion contractures of the ankle are common. Splintage in the resting position is maintained until active movement is achieved. Regular monitoring in physical therapy is maintained until optimal restoration of gait.
Late reconstruction in the presence of subsequent deformity includes the following:
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