Orbital hypertelorism is not a syndrome, but a physical finding in many craniofacial anomalies. It is defined as an increase in the bony interorbital distance. The ethmoid sinuses are normally over-expanded and in some cases of severe hypertelorism, there is an inferior displacement of the cribriform plate.
The midface is in some cases affected with an inverted V-shaped occlusal plane in the maxilla.
Etiology It is both etiologically and pathogenetically heterogenous and can be found in patients with: