Craniosynostosis is the premature closure of one or more cranial vault or cranial base sutures. The prematurely closed suture imposes restrictions to the growth of underlying brain, resulting in compensatory growth and expansion of less restricted areas.
Syndromic
Nonsyndromic
Craniosynostosis has been estimated to occur in 1:2000 to 1:2500 births. The distribution between the different synostosis are as follows:
Factors associated with nonsyndromic premature fusion of cranial sutures are as follows:
During the first year of life the brain will triple in size, followed by slower growth until it reaches its full size in the teen age years. Restrictions of this growth may have functional consequences. The most typical ones are listed below.